a Record control number S0031942211004456

a ISSN 0031-9422

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number QV25

b Item number .C93 2011

a Personal name Yalçın, Funda Nuray.

h Medium Electronic Document

a Title Cycloartane glycosides from Astragalus stereocalyx Bornm

c Statement of responsibility, etc Funda Nuray Yalçın, Sonia Piacente, Angela Perrone, Anna Capasso, Hayri Duman, Ihsan Çalıs

c Date of publication, distribution, etc 2011.

b Name of publisher, distributor, etc Elsevier Ltd

a Summary, etc Six cycloartane-type triterpene glycosides were isolated from Astragalus stereocalyx along with six known cycloartane-type glycosides. Their structures were established by the extensive use of 1D and 2D-NMR experiments along with ESIMS and HRMS analysis. Three compounds are based on an aglycon characterized by the occurrence of an unusual hydroxyl group at position 20, whereas three other compounds are based on cycloasgenin C as aglycon, so far reported from Astragalus spp. All the compounds were tested for their cytotoxic activity against a number of cancer cell lines. One compound exhibited activity versus human cervical cancer (Hela) with an IC50 value = 10 lM.

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Pharmacy

a Topical term or geographic name as entry element Astragalus stereocalyx

a Topical term or geographic name as entry element Cycloartane saponins

a Topical term or geographic name as entry element Cycloasgenin C

g Relationship information 2012, 73:119-126

x International Standard Serial Number 00319422

t Title In Phytochemistry

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1016/j.phytochem.2011.09.011